4-Phosphothiophen-2-yl alanine: a new 5-membered analogue of phosphotyrosine.

نویسندگان

  • Matthew Lilley
  • Bezaleel Mambwe
  • Richard F W Jackson
  • Richmond Muimo
چکیده

Polyclonal antibodies raised against 4-phosphothiophen-2-yl alanine 2a, a novel five-membered ring analogue of phosphotyrosine, showed high selectivity for phosphotyrosine and no cross-reactivity with other phosphorylated amino acids. Western blots showed that the polyclonal was similarly effective, but different in selectivity, to a commercially available monoclonal antibody.

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عنوان ژورنال:
  • Chemical communications

دوره 50 66  شماره 

صفحات  -

تاریخ انتشار 2014